efficient_preparative_separation_of_betacypermethrin_stereoisomers_by_supercritical_fluid_chromatography_with_a_twostep_combined_strategy._资料2.Image.Marked.pdf

Page 1 Journal of Separation Science Efficient preparative separation of -cypermethrin stereoisomers by supercritical fluid chromatography with a two-step combined strategy 1 1, * 2 1 2 3, * Yilun Yan , Jun Fan , Yecai Lai , Jianfeng He , Dong Guo , Hui Zhang , Weiguang Zhang1, * 1 School of Chemistry and Environment, South China Normal University, Guangzhou 510006, China 2 Guangdong YanJie Pharmatech Co. Ltd, Guangzhou 510663, China 3 School of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, China * Corresponding authors: Dr. Jun Fan Prof. Dr. Wei-guang Zhang, School of Chemistry and Environment, South China Normal University, Guangzhou 510006, China E-mail addresses: fanj@ (J. Fan), wgzhang@ (W.G. Zhang) Tel./Fax: +86-20 * Corresponding authors. Tel./Fax: +86 20 E-mail addresses: fanj@ (J. Fan); wgzhang@ (W.G. Zhang); huizhang@ (H. Zhang) Received: 10 02, 2017; Revised: 12 01, 2017; Accepted: 12 04, 2017 This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/jssc.201701138. This article is protected by copyright. All rights reserved. Page 2 Journal of Separation Science An efficient two-step method has been developed for the separation of -cypermethrin stereoisomers by supercritical fluid chromatography with polysaccharide chiral stationary phases. With respect to retention, selectivity, and resolution of -cypermethrin, the effects of chiral stationary phases, co-solvents, mobile phases, and column temperature have been studied in detail. Through a two