平喘降气汤治疗支气管哮喘急性发作临床研究.docVIP

平喘降气汤治疗支气管哮喘急性发作临床研究 　　摘 要：目的：探讨平喘降气汤治疗支气管哮喘急性发作临床疗效。方法：把符合入选条件的130例病人随机分成治疗组和对照组各65例，治疗组予以平喘降气汤100mL,1天2次口服；对照组予以博利康尼片2.5mg，1天3次口服，两组均以3周为1个疗程，疗程结束后，观察疗效、 EOS、IgE、FEV1、PEFR等指标变化。结果：(1)治疗组临床疗效有效率为90.77%，对照组有效率为87.69%，两组间临床疗效无显著性差异(P＞0.05)。 (2)治疗组降低血EOS、IgE均明显优于对照组（P0.05）。结论：平喘降气汤治疗支气管哮喘急性发作有较好的临床疗效，显著改善患者肺功能的同时，又能减轻患者气道的炎性反应。 　　关键词：支气管哮喘；中医药疗法；平喘降气汤；临床研究 　　 　　中图分类号：R256.12 　　文献标识码：B文章编号： 　　1673-7717（2008）05-1114-02 　　?? 　　Clinic Study of Pingchuan JiangQi Tang in Treating Asthra Attack 　　?? 　　WANG Hong?xian?（Yiwu Municipal Hospital of TCM,Yiwu 322000,Zhejiang,China 　　）? 　　Abstract： 　　Objective: To assess the efficacy ofPinchuan JianQi Tang in treating asthma attack. Methods: 130 patients with asthma were randomly divided into treating and control groups. There were 65 cases in each group. In treating group, 100mL Pinchuan JianQi Tang liquids were given to each patient each time twice a day.In control group, 2.5mg of Bricanyl tablet was given three times a day.The treatment course was three weeks.Blood level of EOS，IgE and FEV1，PEFR were respectively tested before and after treating.Results: (1)The efficacy in treating group is 90.77%, in control group is 87.69% , there is no obvious difference between the treating and control groups. The treating group can decrease the plasma level of EOS，IgE,however, The control group have no effect on it .Both group have the same effect on improving the FEV1，PEFR. Conclusion: Pinchuan JianQi Tang is effective on asthma attack, and it can relieve the inflamation in the air way. 　　Keywords：asthma；theraphy of TCM；Pinchuan JianQi Tang；Clinic Study 　　 　　支气管哮喘是严重影响人体健康的慢性呼吸道疾病，为常见病、多发病，其发病率近年来有上升趋势，目前，西药通常用β?2-受体激动剂、茶碱类制剂控制支气管哮喘的发作，并且有??多的副作用。笔者用平喘降气汤治疗支气管哮喘积累了丰富的经验，并取得了满意的效果，现报道如下。? 　　 　　1临床资料? 　　 　　1.1支气管哮喘诊断标准 　　按照中华医学会1997年《支气管哮喘防治指南》诊断标准[1]。? 　　1.2 哮证轻重分度标准 　　参照《中药新药临床研究指导原则》[2]。? 　　1.3 病例纳入标准 　　（1）符合西医支气管哮喘的诊断标准;（2）属于急性发作期轻、中度患者；（3）年龄在16~65岁之间。? 　　1.4 病例排除标准 　　支气管哮喘病情属重度及危重者；年龄小于16岁，大于65岁；有其他系统慢性疾病或合并其他