基因组学试卷(英文).pdfVIP

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基因组学试卷(英文)

Section A - Cells and macromolecules 1 The glycosylation of secreted proteins takes place in the . . . A mitochondria. B peroxisomes. C endoplasmic reticulum. D nucleus. 2 Which of the following is an example of a nucleoprotein? A keratin. B chromatin. C histone. D proteoglycan. 3 Which of the following is not a polysaccharide? A chitin. B amylopectin. C glycosaminoglycan. D glycerol. 4. Transmembrane proteins A join two lipid bilayers together. B have intra- and extracellular domains. C are contained completely within the membrane. D are easily removed from the membrane. Section B - Protein structure 1. Which of the following is an imino acid? A proline. B hydroxy lysine. C tryptophan. D histidine. 2 Protein family members in different species that carry out the same biochemical role are described as . . . A paralogs. B structural analogs. C heterologs. D orthologs. 3. Which of the following is not a protein secondary structure? A -helix. 1 B triple helix. C double helix. D ß-pleated sheet. 4 In isoelectric focusing, proteins are separated . A in a pH gradient. B in a salt gradient. C in a density gradient. D in a temperature gradient. 5 Edman degradation sequences peptides . . . A using a cDNA sequence. B according to their masses. C From the C-terminus to the N-terminus. D from the N-terminus to the C-terminus. Section C - properties of nucleic acids 1 The sequence 5-AGTCTGACT-3 in DNA is equivalent to which sequence in RNA? A 5-AGUCUGUGACU -3 B 5 -UGTCTGUTC -3 C 5 -UCAGUCUGA-3 D 5- AGUCAGACU-3 2. Which of the following correctly describes A-DNA? A a right-handed antiparallel double helix with 10 bp/turn and bases lying perpendicular to the helix axis. B a left-handed antiparallel double-helix with 12 bp/turn formed from

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