热固耦合式超声骨强度仪的可重复性及相关性分析-repeatability and correlation analysis of thermo-solid coupling ultrasonic bone strength instrument.docx

英文缩略词表英文简称英文全称中文全称 OPosteoporosis骨质疏松症BMDbone mineral density骨矿物质密度SPAsingle photon absorptiometry单光子吸收法DPAdouble photon absorptiometry双光子吸收法 DEXAdualenergy X-ray absorptiometry双能 X 吸收法 QCTquantitative computed tomography定量计算机体层摄影 QMRIquantitative magnetic resonance imaging定量磁共振成像 QUSquantitative ultrasound定量超声 SOSspeed of sound声速 BUAbroadband ultrasound attenuation宽带超声衰减 ROCreceiver operating curve工作者受试曲线 SDstandard deviation标准差HRTHormone Replacement Therapy激素替代疗法BMIbody mass index体质数 CVRMS%percentages root-mean square of coefficient of variation变异系数均方根百分比ANOVAanalysis of variance方差分析TItransmission index传输指数热固耦合式超声骨强度仪的可重复性及相关性研究中文摘要目的评估一款国产热固耦合式超声骨强度仪的可重复性和有效性。 方法选择 11 位志愿者，用该仪器测得右跟骨的两个超声参数，分别是超声速度 (SOS)和宽带超声衰减(BUA)，计算每个参数的变异系数均方根百分比（CVRMS%）， 评估该仪器的短期可重复性；选择 18 位志愿者，用类似的方法评估该仪器的中 期可重复性；选择 29 位志愿者，用双能 X 线吸收法（DEXA）测量腰椎骨密度（BMD）， 与该仪器测得的跟骨 SOS,BUA 值进行相关性分析，评估该仪器的有效性。结果（1）超声参数 SOS,BUA 的短期 CVRMS%分别为 0.30，4.24；中期 CVRMS%分别为 0.41，4.20。（2）SOS 与腰椎 BMD 的相关系数 r=0.486（P0.01），BUA 与腰椎 BMD 的相关系数 r=0.629（p0.01）。结论与国际主流定量超声检测仪器相比，热固耦合式超声骨强度仪具有较高的可 重复性和准确性，可用于临床骨质状况评估。关键词骨强度 定量超声 可重复性 相关性 双能 X 线吸收法 超声速度 宽带超声衰减Repeatability and correlation of the warm-air and solid Coupled mode ultrasound bone strength deviceAbstract ObjectivesTo evaluate the repeatability and efficiency of warm-air and solid coupled mode ultrasound bone strength device made in China.MethodsEleven and eighteen volunteers right calcaneus ultrasound parameters, speed of sound (SOS) and broadband ultrasound attenuation(BUA), were detected with the device, percentages root-mean square of coefficient of variation (CVRMS%) of ultrasound parameters were calculated respectively, and used to assess the short- and middle-term repeatabilityofthedevice;29volunteersrightcalcaneusultrasound parameters(SOS,BUA) were detected with the device and bone mineral density(BMD) of lumbar spine were detected with dual energy X-ray absorptiometry (DEXA), The values of correlation coefficient were used to assess the efficiency of the device.