血管紧张素ⅱ与高血压及其代谢性危险因素关系-relationship between angiotensin ⅱ and hypertension and its metabolic risk factors.docxVIP
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血管紧张素ⅱ与高血压及其代谢性危险因素关系-relationship between angiotensin ⅱ and hypertension and its metabolic risk factors
血管紧张素II与高血压及其代谢性危险因素的关系中文摘要性,结果显示:不管是单因素还是多因素Logisitic回归分析,高TC、高LDL-C和低HDL-C与研究对象中AngII升高的关联都无统计学意义,P0.05。但是对于高TG,调整年龄、性别、吸烟、饮酒、血压、血糖、胰岛素、BMI、腰围后,高TG患者AngII升高的危险性是正常人群的1.51倍,趋势性检验结果显示,随着TG水平的增加,AngII升高的可能性就越大,P0.05。结论1..高血压患者、胰岛素抵抗患者、高甘油三脂患者中AngII浓度高于正常人群,AngII增高与高血压、胰岛素抵抗和高甘油三酯有关联。2.对于该研究人群,未发现AngII与糖尿病、超重与肥胖和血脂异常中高胆固醇、低-高密度脂蛋白和高-低密度脂蛋白的关联。关键词:血管紧张素Ⅱ;高血压;代谢性危险因素作者:韦晓淋指导教师:张永红英文摘要血管紧张素II与高血压及其代谢性危险因素的关系RelationofangiotensinIIwithhypertensionanditsmetabolicriskfactorsAbstractBackgroundTheincidenceofhypertensionisoftenaccompaniedwithavarietyofmetabolicabnormalities.Currently,relationshipsbetweenAngiotensinII(AngII)andmetabolicriskfactorsofhypertensionarerarelyreportedandnotyetconclusivebothathomeandabroad.PurposeThisthesisisaimedatexploringtherelationshipsbetweenAngIIandhypertensionaswellasitsmetabolicriskfactors(highbloodglucose,insulinresistance,overweightandobesity,dyslipidemia)inMongolian;TheresultscanprovideanewwayoftargetingAngIIforthefuturetreatmentofcombinedhypertension,suchasobesity.method2559Mongolianordinarilyresidentsaged20yearsandabovewerestudied,andknownpatientsofstroke,coronaryheartdisease,andkidneypatientswereexcluded.Usingcross-sectionalsurvey,dataondemographiccharacteristics,historyofdiseasesandlifewayriskfactorswerecollectedandbloodpressure,heightandweight,waistcircumferenceweremeasured.Thebloodsampleswerecollectedinsiteandwerecryopreservedandtransportedtothelaboratoryfordetectionofcholesterol,triglycerides,high-densitylipoprotein,low-densitylipoprotein,glucose,insulin,AngIIandotherindicators.TheindicatorswererecordedintoEpidatadatabasedoubletimesbytwopersons,andanalyzedbySPSS16.0software.ThedifferencesofdemographiccharacteristicsandmetabolicriskfactorsofhypertensionbetweenthenormalAngIIgroupandtheincreasedAngIIgroupwerecompared,andtherelationshipsbetweendifferentAngIIlevelsandhypertensionaswellasitsmetabolicriskfactors(highbloodglucose,insulinresistance,overweightandobesity,dyslipidemia)wereanalyzed血管紧张素II与高血压及其代谢性危险因素的关系英文摘要byusingsingleandmultipl
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