医学的重大发现——人体解剖.pptVIP

Most oncogenes require an additional step, such as mutations in another gene, or environmental factors, such as viral infection, to cause cancer. Since the 1970s, dozens of oncogenes have been identified in human cancer. A proto-oncogene is a normal gene that can become an oncogene due to mutations or increased expression. The first oncogene was discovered in 1970 and was termed src. Src was in fact first discovered as an oncogene in a chicken retrovirus. Experiments performed by Dr G. Steve Martin of the University of California, Berkeley demonstrated that the SRC was indeed the oncogene of t