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Ultrasound Elastography Prostate Cancer Detection :超声弹性成像前列腺癌的检测
* * Ultrasound Elastography: Prostate Cancer Detection Assessment Using A Phantom Brett Coelho Medical Biophysics 3970Z March 26, 2013 Introduction Prevalence and Early Detection Ultrasound Elastography Specificity and Sensitivity B-mode Prostate Image Introduction Stiffness Strain Images B- mode Image Strain Image Methods Hooke’s Law Young’s Modulus Reconstruction: Iterative Methods Phantom Construction Phantom Ingredients Methods Preparing Phantom Solutions Gelatin – 70 Agar – 80 Formaldehyde – 90 Glycerol – 90 Sigma Cell Cool Down Methods Pouring The Moulds Prostate and Surrounding Tissue Moulds Tumor Moulds Methods Pouring The Moulds Prostate and Sample Moulds Methods Uniaxial Test Uniaxial Testing Machine and Cylindrical Sample Methods Ultrasound Circular Ultrasound Array Linear Array Methods Strain Images Strain Imaging Results Uniaxial Results Ratios Ep/Es=5.4 Et1/Es=8.7 Et2/Es = 9.3 Strain Stress kPa Results Post Processing Elastic Moduli Reconstruction Strain Image Frames Results Post Processing Ep/Es=2.2 Et1/Es=6.0 Et2/Es=8.9 Phantom Tissue Manual Selections Results Tumour Mis Allocations TM1=5.21 TM2=5.68 Reconstructed Image Tumor Locating B-mode Image Tumor Locating Conclusions Comparing the ratios Tumor Misallocations Sources of Error Strain Images Uniaxial Test Assumptions for Stress Calculation Future Research Improve Detection and Modulus Calculations Computational Time Assumptions and Meshing Acknowledgements Dr. Samani Reza Mousavi Thank you! * * * * * * * * * * * * * * * * * * * * * * * * * * *
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