抗生素与耐药（英文PPT）Antibiotics and Antibiotic .pptVIP

AntibioticsAntibiotic resistance Animations from lecture Protein synthesis inhibitors Inhibit translocation (prevent ribosome from moving to the next codon) Inhibit peptide-bond formation Block the growing chain by linking to the peptide Inhibit binding of aa-tRNAs (charged tRNAs) Cause misreading of codons Initiation of translation in bacteria Aminoglycosides Interfering with the Translocation of tRNA from the A-site to the P-site Aminoglycosides (streptomycin, neomycin, netilmicin, tobramycin, gentamicin, amikacin, etc) Mode of Action of Macrolides in BlockingTranslation: Blocking Peptidy