Blood group systems-ISBT血型系统.docxVIP

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Blood group systems-ISBT血型系统

Blood group systemsISBT№System nameSystem symbolEpitope?or carrier, notesChromosome001ABOABOCarbohydrate (N-Acetylgalactosamine,?galactose). A, B and H antigens mainly elicit?IgM?antibody reactions, although anti-H is very rare, see the?Hh antigen system?(Bombay phenotype, ISBT #18).9002MNSMNSGPA / GPB (glycophorins?A and B). Main antigens M, N, S, s.4003PP1Glycolipid. Antigen P1.22004Rh?(Rhesus)RHProtein. C, c, D, E, e antigens (there is no d antigen; lowercase d indicates the absence of D).1005LutheranLUProtein (member of the?immunoglobulin superfamily). Set of 21 antigens.19006KellKELGlycoprotein. K1?can cause?hemolytic disease of the newborn (anti-Kell), which can be severe.7007LewisLECarbohydrate (fucose?residue). Main antigens Lea?and Leb?- associated with tissue ABH antigen secretion.19008DuffyFYProtein (chemokine receptor). Main antigens Fya?and Fyb. Individuals lacking Duffy antigens altogether are immune to?malariacaused by?Plasmodium vivax?and?Plasmodium knowlesi.1009KidddbMHCProtein (urea transporter). Main antigens Jka?and Jkb.18010DiegoDIGlycoprotein (band 3, AE 1, or anion exchange). Positive blood is found only among?East Asians?and?Native Americans.17011Yt or CartwrightYTProtein (AChE,?acetylcholinesterase).7012XGXGGlycoprotein.X013SciannaSCGlycoprotein.1014DombrockDOGlycoprotein (fixed to cell membrane by GPI, or?glycosyl-phosphatidyl-inositol).12015ColtonCOAquaporin 1. Main antigens Co(a) and Co(b).7016Landsteiner-WienerLWProtein (member of the?immunoglobulin superfamily).19017Chido/RodgersCH/RGC4A C4B (complement fractions).6018Hh/BombayHCarbohydrate (fucose?residue).19019KxXKGlycoprotein.X020GerbichGEGPC / GPD (Glycophorins?C and D).2021CromerCROMGlycoprotein (DAF or?CD55, regulates complement fractions C3 and C5, attached to the membrane by GPI).1022KnopsKNGlycoprotein (CR1 or?CD35, immune complex receptor).1023IndianINGlycoprotein (CD44?adhesion function?).11024OkOKGlycoprotein (CD147).19025RaphMER2Transmembrane glycoprotein.11026JMHJMHProtein

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