碳复合材钙磷胶原涂层的研究毕业设文.docVIP

碳/碳复合材料钙磷/胶原涂层的研究 摘 要 碳/碳复合材料的弹性模量与骨非常接近, 同时具有优越的生物相容和生物力学性能，作为骨修复和骨替换材料，极具有应用前景。但其为惰性生物材料，不能引导或诱导骨组织形成，为使其具有生物活性，可在其表面制备生物活性涂层。制备生物活性涂层的众多方法中，电化学沉积法因其反应条件温和，可获得高生物活性的羟基磷灰石涂层，同时该方法具有操作简单，可控性强，成本低廉等优点。但使用此方法制备的涂基结合强度不高，为改善涂基结合强度，本文采用电沉积制备碳/碳复合材料羟基磷灰石涂层，在前人研究的电解液的浓度、电极距离、沉积电压、液位高度、超声频率、超声功率对钙磷涂层的组成、结构和表面形貌影响的基础上，对碳/碳复合材料表面进行氧化处理并制备了钙磷涂层，然后在人体模拟体液中浸泡研究，主要的研究内容如下： 本文采用阳极氧化处理碳/碳复合材料后，通过电沉积的方法在碳/碳复合材料表面制备CaP、CaP/col、HA/col三种涂层，然后进行人体模拟体液浸泡实验，通过质量变化量，PH变化曲线，EDS数据，扫描电镜（SEM），钙磷粒子浓度等分析手段，探讨了三种涂层的生物活性。 研究结果表明：随着CaP涂层在人体模拟体液中浸泡时间的增加，涂层的质量也随之增大，CaP涂层可在人体模拟体液中诱导含碳酸根羟基磷灰石的形成，CaP生物涂层具有较好的生物活性；随着CaP/col和HA/col两种涂层在人体模拟体液中浸泡时间的增长，两种涂层的质量也在逐渐增大，两种涂均层可在人体模拟体液中诱导含碳酸根羟基磷灰石的形成，CaP/col和HA/col两种涂层均具有良好的生物活性，有利于促进碳/碳复合材料的骨性结合。 关键词：碳/碳复合材料，电沉积，生物涂层，生物活性 The carbon/carbon composites calcium phosphate/collagen coating research Abstract The carbon/carbon composites with elastic modulus, and very close to the bone with superior biocompatible and biomechanical properties, as the bone repair and replacement, extremely has the bone material application prospect. But it is inert, cannot lead or biological materials for bone tissue, induced by its bioactive in its surface preparation, bioactive coating. Preparation of bioactive coating method, electrochemical deposition for its mild reaction condition, can obtain high biological activity of hydroxyapatite coating, at the same time, this method has simple operation, low cost control, etc. But this method of preparation TuJi strength is not high, to improve the bonding strength, this paper TuJi ultrasonic electrochemical deposition carbon/carbon composites hydroxyapatite coating on the previous research, the concentration of electrolyte, electrode distance, sedimentary voltage, frequency and high level of ultrasonic power, ultrasonic of calcium phosphate coated composition, structure and surface morphology, on the basis of the influence of carbon/carbon composites surface oxidation process and the preparation of calcium phosphate coated. The main