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Instructions for SAS v. 9.2 aSummaryStats8.sas The Minimum C Method Troubleshooting * Save the programs to a common folder: Make sure to retain (i.e. copy) the “FileFolder” which is required by other programs in order for them to work properly. In the instructions, the FileFolder is “I:\Example” Program Summary Alpha Restriction.sas – Searches for critical values using the “alpha restricted method” over 1st and 2nd stage sample sizes with ranges specified by the user. amacros.sas – contains a set of macros utilized by other programs. aSummaryStats8.sas – is an algorithm that searches for a design that meets the user’s specifications, looking at average power similar to Chen and Ng (1998), over 8x8=64 accrual combinations. aSummaryStats8_min.sas – is an algorithm that searches for a design that meets the user’s specifications, requiring user specified minimum power over all accrual combinations. Dependent.sas – Characterizes the design under the case of associated (correlated) responses (i.e. Xr is not independent of Xs). The Minimum C.sas – Searches for critical values using the “Minimum C Method.” SummaryStats8_C.sas – is an algorithm that searches for a design that meets the user’s specifications, based on designs that use The Minimum C Method. (1) Decide Which Method to Use: The Alpha Restriction or The Minimum C An Example the Alpha Restriction Method Is Provided Below: You can enter the values of the parameters directly into the program. Since Greek letters are not accepted by the software, , etc. which are explicitly defined in the program introduction (not shown). The values of n1L, n1U, nL, and nU should encompass the anticipated sample sizes for stage 1 and 2. Don’t forget to provide the location of the “FileFolder” where the programs are located. Alternatively, the user can specify the parameters or change them after the program is run. Open Alpha Restriction.sas using SAS software: Running the program allows the user to explicitly see