降钙素原与C反应蛋白联合检测在成人下呼吸道感染中临床价值.docVIP

降钙素原与C反应蛋白联合检测在成人下呼吸道感染中临床价值 　　[摘要] 目的 评价检测降钙素原（PCT）与C反应蛋白（CRP）水平对成人下呼吸道感染诊断的临床意义。 方法 52例细菌感染下呼吸道感染患者血清PCT、CRP的含量及动态变化进行检测，按不同感染类型分类比较降钙素原水平的差异。 结果 细菌感染组（8.9±1.2）ng/mL，非细菌感染组（0.1±0.09）ng/mL，两组比较差异有统计学意义（P 0.05）。对细菌培养阳性病例进行APACHE评分存在正相关性（r = 0.58，P = 0.02）。 结论 血清PCT、CRP联合检测在细菌感染的早期诊断中有一定价值，动态监测PCT水平有助于评估治疗效果。 　　[关键词] 降钙素原；C反应蛋白；细菌感染 　　[中图分类号] R56 [文献标识码] B [文章编号] 1673-9701（2013）07-0088-02 　　Application of the determination of serunl procaldtonin and C reactive protein in patient with lower respiratory infection 　　GAO Min1 LI Chongjin2 ZENG Baihua1 　　1.Microbiology Laboratory， Department of Clinical Laboratory， the Peoples Hospital of Mianyang City in Sichuan Province， Mianyang 621000， China； 2.Department of Clinical Laboratory， the Peoples Hospital of Mianyang City in Sichuan Province， Mianyang 621000， China 　　[Abstract] Objective To evaluate the clinical value of procalcitonin （PCT） and C-reactive protein （CRP） on the diagnosis of adult respiratory infections. Methods A total of 52 cases of bacterial infections of lower respiratory tract infections was detdected PCT， CRP corroding to classification according to the different types of infection， and to compare with infection group. Results of bacterial infection group （8.9±1.2）ng/mL， non-bacterial infection group （0.1±0.09）ng/mL， the difference was statistically significant （H = 18.12， P = 0.012）. Bacterial infection subgroup analysis of different types of infection sepsis group， hospital-acquired infection group， the reorganization of acute exacerbations of chronic obstructive pulmonary disease and non-bacterial infection group， the difference was statistically significant （P 0.05） compared with non-bacterial. APACHE score and the procaldtonin levels suggesting that there is a positive correlation （r = 0.58， P = 0.02）. Conclusion Serum PCT and CRP joint detection in the early diagnosis of bacterial infections had a useful index to evaluate the lower respiratory infection. 　　[Key words] Procalcitonin； C-re