Brucella suis Iowa State University布氏杆菌病布氏是爱荷华州立大学课件.ppt

Acknowledgments Development of this presentation was made possible through grants provided to the Center for Food Security and Public Health at Iowa State University, College of Veterinary Medicine from the Centers for Disease Control and Prevention, the U.S. Department of Agriculture, the Iowa Homeland Security and Emergency Management Division, and the Multi-State Partnership for Security in Agriculture. Authors: Kerry Leedom Larson, DVM, MPH, PhD, DACVPM; Anna Rovid Spickler, DVM, PhD; Sarah Viera, MPH Reviewer: Glenda Dvorak, DVM, MPH, DACVPM Center for Food Security and Public Health, Iowa State University, 2012 * In today’s presentation we will cover information regarding the organism that causes brucellosis in swine and its epidemiology. We will also talk about the history of the disease, how it is transmitted, species that it affects (including humans), and clinical and necropsy signs observed. Finally, we will address prevention and control measures for swine brucellosis, as well as actions to take if swine brucellosis is suspected. [Photo: Sow and piglets. Source: Scott Bauer/USDA ARS] * In pigs, brucellosis is mainly caused by Brucella suis, a Gram negative coccobacillus or short rod. This organism is a facultative intracellular pathogen. Other Brucella species rarely found in pigs include Brucella abortus and B. melitensis . B. suis contains more diverse isolates than other Brucella species, and these isolates have broader host specificity. Five B. suis biovars have been identified. Biovars 1, 2 and 3 are maintained in pigs; European hares are also a reservoir for biovar 2. Biovar 4 mainly affects reindeer and caribou and is not normally found in pigs, although is genetically very closely related to biovar 1. Biovar 5 occurs in rodents in the former USSR. Biovar 5 is distinct from other B. suis biovars, and may be more closely related to marine mammal Brucella isolates. Brucella species can persist in the environment invariably depending on te