皮肤药动学研究中若干值得注意的问题.pptVIP

Announcements I It is not clear about the sample collection time in the absorption phase and elimination phase of drug and need repeated tests. A lot of sticky tapes are needed for collecting fully samples of the stratum corneum. It is not clear whether the stratum corneum collected samples of the first two should be discarded,which needs for rigorous investigation. The changes of subjects’ skin condition (hydration, body temperature) and experimental conditions (humidity, temperature) will affect the test results. Announcements II It will need further whether the concentration of the d