临床医学专业-慢性粒细胞白血病双语.pptVIP

healthy physical examination and found the white blood cells increased. 患者，马**，男，54岁，主因“体检发现白细胞增高，脾脏肿大1周”入院。 查体：皮肤、巩膜无黄染，浅表淋巴结无肿大，胸骨压痛+，脾大平脐，质中等 * * Is a kind of malignant myeloproliferative disease happened in the early pluripotent hematopoietic stem cells phase is mainly concerned with myeloid development, develops relatively slow. * It occurs at all ages (incidence of 1 cases/million population, median age 50-60 years, male/female ratio equal) The important landmarks in the study of CML were the discovery of the Philadelphia (Ph) chromosome and the characterization of the BCR–ABL fusio