Influence of the β_Sheet Content on the Mechanical.pptxVIP

Influence of the β-Sheet Content on the Mechanical Properties of Aggregates during Amyloid Fibrillization;Background;Peak force quantitative nanomechanical mapping (PF-QNM) The values of the Young’s moduli of different classes of mature amyloid fibrils;Results;Secondary-structure of α-synuclein(c) and Aβ42(d);AFM imaging of the a-synuclein and Aβ-42 fibrillization process;Evolution of the Young’s modulus of α-synuclein during the fibrillization process.;Evolution of the Young’s modulus of Aβ-42 during the fibrillization process;Conclusion