染色体数值偏差模式在乳头状肾细胞癌评论文章：（Chromosomal numerical aberration pattern in papillary renal cell carcinoma Review article）.pdfVIP

Annals of Diagnostic Pathology xxx (xxxx) xxx–xxx Contents lists available at ScienceDirect Annals of Diagnostic Pathology journal homepage: /locate/anndiagpath Review Articles Chromosomal numerical aberration pattern in papillary renal cell carcinoma: Review article☆ a b c b,⁎ Tomas Pitra , Kristyna Pivovarcikova , Reza Alaghehbandan , Ondrej Hes a Department of Urology, Charles University, Medical Faculty, Charles University Hospital Plzen, Czech Republic b Department of Pathology, Charles University, Medical Faculty, Charles University Hospital Plzen, Czech Republic c Department of Pathology, Faculty of Medicine, University of British Columbia, Royal Columbian Hospital, Vancouver, BC, Canada A R T I C L E I N F O A B S T R A C T Keywords: Traditionally, papillary renal cell carcinomas (PRCCs) have been divided in two subgroups – type 1 and type 2. Kidney Based on recent molecular and genetic developments in the understanding of RCCs, it seems that this traditional Papillary renal cell carcinoma classification may not be adequate and that the spectrum of PRCCs is much wider than initially proposed. Small Chromosomal numerical aberration pattern series of distinct types of PRCC which do not fit into the above mentioned categories have been described in the Review literature. Published studies investigating molecular genetic changes in various types of PRCCs have sho