消化性溃疡 中山大学 内科学ppt课件.ppt

Diseases of the Stomach and Duodenum;;“If there is no acid, peptic ulceration cannot occur.” In fact, peptic ulcers may occur anywhere where pepsin and acid occur together . They may occur in the esophagus, the duodenum, the stomach itself, the jejunum after surgical construction of a gastrojejunostomy, or in the Meckel’s diverticulum .;Peptic Ulcer Disease;DU and GU;PU is caused by an imbalance between secretion of acid and pepsin, and breakdown of mucosal defence. An acid environment and reduced mucosal defences provide ideal circumstances for pepsin to cause mucosal ulceration.;;Over-excit