慢性淋巴细胞性甲状腺炎医学课件.pptVIP

*;内 容;Dr. Hakaru Hashimoto ;概 述;;分型;流行病学;病因和发病机制;与硒缺乏的相关性;25羟维生素D3与甲状腺疾病相关性;病 理;Figure?1.?The TAZ10 transgenic mouse model10 and the immunological basis for Hashimoto thyroiditis.(a) Thyroid follicle and the location of the major thyroid autoantigens: thyroid peroxidase (TPO), thyroglobulin (Tg) and the thyroid-stimulating hormone receptor (TSHR). (b) Immunological mechanisms leading to the spectrum of human autoimmunity with differing pathological and clinical characteristics. Graves hyperthyroidism is caused directly by TSHR autoantibodies that activate the TSHR. Hypothyroidism in Ha