0.05%丙酸氟替卡松乳膏治疗湿疹临床疗效观察.docVIP

0.05%丙酸氟替卡松乳膏治疗湿疹的临床疗效观察 　　[摘要] 目的:观察0.05%丙酸氟替卡松乳膏治疗湿疹的临床疗效。方法:将我院收治的55例湿疹患者随机分为两组,观察组28例患者采用0.05%丙酸氟替卡松乳膏治疗,对照组27例患者采用0.1%丁酸氢化可的松软膏治疗,比较分析两组的疗效。结果:观察组总有效率为92.9%,对照组为66.7%,两组间有显著性差异(χ2=5.892 8,P0.05),两组均无明显不良反应发生。结论:0.05%丙酸氟替卡松乳膏治疗湿疹疗效满意,且不良反应少,值得临床关注。 　　[关键词] 湿疹;丙酸氟替卡松乳膏;丁酸氢化可的松软膏 　　[中图分类号]R758.23 [文献标识码]B [文章编号]1673-7210(2010)03(a)-055-02 　　 　　Clinical observation of 0.05% Fluticasone Propionate in the treatment of eczema 　　WU Zhijian 　　(Dermatosis Dispensary of Foshan City,Guangdong Province, Foshan 528000, China) 　　[Abstract] Objective: To investigate the clinical effect of 0.05% Fluticasone Propionate in the treatment of eczema. Methods: 55 patients of eczema were randomly divided into two groups, the observation group (28 cases) were treated by 0.05% Fluticasone Propionate, the control group (27 cases) were treated by 0.1% Hydrocortisone Butyrate Ointment. The efficacy of the two groups were observed and compared. Results: The total effective rate in observation group was 92.9% and that in the control group was 66.7%. There was a significant difference between the two groups (χ2=5.8928,P0.05). There were no obvious adverse reactions in the two groups. Conclusion: 0.05% Fluticasone Propionate in the treatment of eczema has satisfactory curative effect and fewer complications, it is worth popularizing. 　　[Key words] Eczema; Fluticasone Propionate; Hydrocortisone Butyrate Ointment 　　 　　湿疹(eczema)是一种常见的由多种内外因素引起的表皮及真皮浅层的炎症性皮肤病,多认为与变态反应有一定关系,其临床表现具有对称性、渗出性、瘙痒性、多形性和复发性等特点。它也是一种过敏性炎症性皮肤病,以皮疹多样性、对称分布、剧烈瘙痒反复发作、易演变成慢性为特征。我院采用0.05%丙酸氟替卡松乳膏治疗该病获得满意疗效,现将相关临床资料总结报道如下: 　　1 资料与方法 　　1.1 一般资料 　　选择我院2008年7月～2009年4月收治的湿疹患者55例,所有患者的诊断均符合《临床皮肤病学》标准[1]:皮损增厚、浸润棕红色或灰色,色素沉着,表面粗糙,覆以少许鳞屑,可有不同程度苔藓样变,外周可有丘疹、丘疱疹;自觉症状瘙痒;具局限性,可发于身体任何部位;病程呈慢性;排除心、肝、肾疾患、糖尿病患者,以及合并其他皮肤病患者。其中,男30例,女25例,年龄19～58岁,平均41.5岁,病程3个月～8年,平均3.5年。将所有患者随机分为观察组28例和对照组27例,两组患者的一般资料比较,无显著性差异(P0.05),具有可比性。 　　1.2 方法 　　观察组28例患者采用0.05%丙酸氟替卡松乳膏治疗,涂于患处薄薄的一层,轻揉按摩2 min左右,每日2次。对照组27例患者采用0.1%丁酸氢化可的松软膏治疗,用法同观察组。对所有患者每周随访1次