CA125IL―6VEGF对子宫内膜异位症诊断价值.docVIP

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CA125IL―6VEGF对子宫内膜异位症诊断价值.doc

CA125IL―6VEGF对子宫内膜异位症诊断价值

CA125IL―6VEGF对子宫内膜异位症诊断价值   【摘要】 目的:探讨癌抗原125(CA125)、白细胞介素-6(IL-6)、血管内皮生长因子(VEGF)对子宫内膜异位症的诊断价值。方法:选择笔者所在医院2016年10月收治的65例子宫内膜异位症患者,同期选择65例体检健康者作为健康组,比较两组CA125、IL-6、VEGF水平,以及子宫内膜异位症患者治疗前后CA125、IL-6、VEGF水平。结果:子宫内膜异位症组CA125、IL-6、VEGF水平显著高于健康组,且子宫内膜异位症患者治疗后CA125、IL-6、VEGF水平均低于治疗前,差异均有统计学意义(P0.05)。结论:通过检测CA125、IL-6、VEGF水平能够利于子宫内膜异位症的诊断,指导临床治疗。   【关键词】 子宫内膜异位症; 癌抗原125; 白细胞介素-6; 血管内皮生长因子   doi:10.14033/j.cnki.cfmr.2017.27.043 文献标识码 B 文章编号 1674-6805(2017)27-0080-02   Value of CA125,IL-6,VEGF in Diagnosis of Endometriosis/CHAI Lin.//Chinese and Foreign Medical Research,2017,15(27):80-81   【Abstract】 Objective:To research the value of CA125,IL-6,VEGF in diagnosis of endometriosis.Method:In October 2016,65 cases of endometriosis were selected,65 cases of healthy physical examination for the same period were selected as the healthy group,CA125,IL-6,VEGF levels and CA125,IL-6,VEGF before and after the treatment were compared between the two groups.Result:The CA125,IL-6,VEGF in the endometriosis group were significantly higher than those in the healthy group,CA125,IL-6,VEGF levels after treatment were significantly lower than before treatment,the differences were statistically significant(P0.05).Conclusion:Through the detection of CA125,IL-6 and VEGF levels can be conducive to the diagnosis of endometriosis,guide clinical treatment.   【Key words】 Endometriosis; Cancer antigen 125; Interleukin-6; Vascular endothelial growth factor   First-author’s address:Zhejiang University Medical College Affiliated Obstetrics and Gynecology Hospital,Hangzhou 310000,China   子?m内膜异位症作为妇科常见疾病,大部分患者可出现继发性痛经、不育、性交痛、月经改变等典型临床表现,严重影响患者的生活质量[1-2]。子宫内膜异位症虽为良性病变,但存在局部浸润生长和转移等恶性肿瘤的能力,及时诊治有着重要临床价值。临床研究指出血清癌抗原125(CA125)、白细胞介素-6(IL-6)、血管内皮生长因子(VEGF)水平与病变程度有着紧密联系[3-4]。本研究就探讨CA125、IL-6、VEGF对子宫内膜异位症的诊断价值。   1 资料与方法   1.1 一般资料   选择笔者所在医院2016年10月收治的65例子宫内膜异位症患者,纳入标准:经临床诊断为子宫内膜异位症;月经比较规律;既往未见其他代谢性、免疫及内分泌疾病;近3个月内无激素治疗史。排除标准:伴盆腔感染、子宫肌瘤等妇科疾病;恶性肿瘤;肝肾等功能异常;子宫内膜异位症复发者[5]。年龄22~40岁,平均(31.48±2.36)岁。同期选择65例体检正常者作为

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