2012更年期激素疗法一级预防慢性疾病建议-美国预防医学工作组建议声明.pdf

***ONLINE FIRST: This version will differ from the print version*** Annals of Internal Medicine Clinical Guideline Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions: U.S. Preventive Services Task Force Recommendation Statement Virginia A. Moyer, MD, MPH, on behalf of the U.S. Preventive Services Task Force* Description: Update of the 2005 U.S. Preventive Services Task of menopausal symptoms, such as hot flashes or vaginal dryness. It Force (USPSTF) recommendation statement on hormone therapy also does not apply to women younger than 50 years who have for the prevention of chronic conditions in postmenopausal women. had surgical menopause. Methods: The USPSTF commissioned a review of the literature to Recommendation: The USPSTF recommends against the use of update evidence about the benefits and harms of using meno- combined estrogen and progestin for the prevention of chronic pausal hormone therapy to prevent chronic conditions, as well as conditions in postmenopausal women. (Grade D recommendation). whether the benefits and harms of hormone therapy differ by The USPSTF recommends against the use of estrogen for the population subgroups defined by age; the presence of comorbid prevention of chronic conditions in postmenopausal women who medical conditions; and the type, dose, and method of hormonal have had a hysterectomy. (Grade D recommendation). delivery. Ann Intern Med. 2013;158:* * * FILL THIS IN * * *. n Population: This recommendation applies t