乳腺癌保乳治疗预后分析.docVIP

乳腺癌保乳治疗预后的分析 　　【摘要】 目的：探析乳腺癌保乳治疗的预后分析。方法：选取本院2013年1月-2014年1月乳腺癌患者100例，按治疗方式的不同分为观察组、对照组，每组各50例。观察组进行保乳治疗，即乳腺区段切除或肿块扩大切除+腋窝淋巴结清扫术；对照组进行乳腺癌改良根治术+腋窝淋巴结清扫术，比较两组患者的复发情况、转移情况及生存率情况。结果：观察组乳房美容效果优秀27例（54.0%），良好13例（26.0%），一般9例（18.0%），较差1例（2.0%），优良率80.0%（40例）；两组的复发率及转移情况差异无统计学意义（P0.05）；术后观察组、对照组并发症发生率分别为6%、10%，两组比较差异无统计学意义（P0.05）； 两组的术后1、3、5年生存率比较差异无统计学意义（P0.05）。结论：乳腺癌患者进行保乳治疗必须严格掌握其适应证，其生存率、复发转移情况与传统改良根治术比较无显著差异，但美容效果更佳，提高了患者的生活质量，保乳治疗后应注重综合治疗，临床效果确切，值得临床推广。 　　【关键词】 预后分析； 病灶转移； 生存率； 乳腺癌； 保乳治疗 　　【Abstract】 Objective： To analyze breast conserving therapy prognosis for breast cancer. Method：100 cases of patients with breast cancer from January 2013 to January 2014 in our hospital were selected and divided into observation group and control group based on different treatment methods，50 cases in each group. Observation group was given breast-conserving therapy， namely segmental mastectomy or extensive mass resection+axillary lymph node dissection， while control group was given modified radical mastectomy+axillary lymph node dissection. Recurrence， metastasis and survival rate of both groups were compared.Result： Breast cosmetic effect of the observation group： excellent for 27 cases （54.0%）， good for 13 cases （26.0%）， fair for 9 cases （18.0%） and poor for 1 case （2.0%），and good rate of 80.0% （40 cases）； recurrence rate and metastasis differences of both groups were not statistically significant （P0.05）； postoperative complication rates of observation group and control group were respectively 6% and 10%， the difference was not significant （P0.05）； survival rate after 1 year， 3 years， and 5 years of the observation group and control group had no significant difference（P0.05）. Conclusion： Strict indication control is necessary for breast conserving therapy on the treatment of patients with breast cancer. There is no significant difference in survival rate， recurrence， and metastasis with traditional modified radical operation. But its cosmetic results are better， with improvemen