呼气末二氧化碳分压在心肺复苏中应用.docVIP

呼气末二氧化碳分压在心肺复苏中应用 　　[摘要] 目的：探讨呼气末二氧化碳分压（PETCO2）在心肺复苏（CPR）中的临床意义。方法：选取本院急诊科发生心跳骤停并符合入选标准患者54例，依据复苏是否恢复自主循环分为初始复苏成功组和失败组，监测CPR过程中PETCO2的变化。结果：21例患者初始复苏成功；复苏成功组和失败组复苏即刻PETCO2水平差异无统计学意义（P0.05）。两组患者PETCO2水平在复苏开始后5、10 min以及20 min时比较，差异有统计学意义（P0.01）。结论：PETCO2水平与心跳骤停患者心肺复苏的预后相关。 　　[关键词] 呼气末二氧化碳分压；心肺复苏；自主循环恢复 　　[中图分类号] R605.974 [文献标识码]A[文章编号]1674-4721（2010）11（b）-045-02 　　 　　End-tidal carbon dioxide partial pressure during cardiopulmonary resuscitation 　　WANG Yong, CHENG Lishun, MENG Lingyi, XIA Jiadong, DING Wenlian, HU Chenzhi, ZHU Yi, CAI Peng 　　(Department of Emergency, the First People′s Hospital of Hefei City, Anhui Province, Hefei 230061, China) 　　[Abstract] Objective: To investigate the end-tidal carbon dioxide partial pressure(PETCO2) in cardiopulmonary resuscitation (CPR) in clinical significance. Methods: The hospital emergency department cardiac arrest and 54 patients met the inclusion criteria, based on the recovery of spontaneous circulation is restored into the initial resuscitation group and the failure group to monitor the changes PETCO2 during CPR. Results: 21 patients with initial resuscitation; resuscitation immediate resuscitation group and the failure was no significant difference PETCO2 levels (P0.05). PETCO2 two groups of patients in the recovery after the start of the level of 5,10 min and 20 min time, the difference was statistically significant(P0.01). Conclusion: PETCO2 level of CPR in patients with cardiac arrest prognosis. 　　[Key words] End-tidal carbon dioxide partial pressure; Cardiopulmonary resuscitation; Return of spontaneous circulation 　　 　　心肺复苏（cardiopulmonary resuscitation，CPR）是抢救心跳骤停患者的重要方法，临床上判断CPR成功与否通常依据某些体征的变化，如大动脉搏动、瞳孔、皮肤黏膜颜色等，但这些体征的变化不够确切。2005年心肺复苏和心血管急救指南认为呼气末二氧化碳分压（end-tidal carbon dioxide partial pressure，PETCO2）是CPR过程中能够评价CPR效果和预后的无创监护手段。笔者观察54例急诊室内心跳骤停患者心肺复苏过程中PETCO2的变化，探讨其在心肺复苏时的临床意义。 　　1 资料与方法 　　1.1 一般资料 　　入选2008年2月～2009年3月本院急诊科发生心跳骤停患者158例，最终入选患者54例，男34例，女20例，年龄33～101岁，平均（67.20±14.68）岁。 　　1.2 入选标准 　　急诊室内发生