复方异丙托溴铵雾化治疗慢阻肺急性加重期患者临床效果分析.docVIP

复方异丙托溴铵雾化治疗慢阻肺急性加重期患者临床效果分析 　　[摘要] 目的 分析复方异丙托溴铵雾化治疗在慢阻肺急性加重期患者的临床效果。 方法 随机选取2014年5月～2017年5月我院收治的慢阻肺急性加重期患者80例，依据治疗方法将患者分为对照组（布地奈德雾化吸入治疗，n=40）和治疗组（布地奈德+复方异丙托溴铵雾化吸入治疗，n=40），对两组患者的呼吸困难评分、血气分析指标、呼吸功能指标、不良反应发生情况进行统计分析。 结果 治疗组患者的呼吸困难评分、PaCO2水平降低幅度、PaO2水平提升幅度均高于对照组（P0.05），FEV1、FEV1%、FVC提升幅度均显著高于对照组（P0.05）。 结论 复方异丙托溴铵雾化治疗在慢阻肺急性加重期患者的临床效果好，能够有效缓解患者呼吸困难，改善患者血气分析及肺功能，值得推广。 　　[关键词] 复方异丙托溴铵；雾化治疗；慢阻肺；急性加重期 　　[中图分类号] R563.9 [文献标识码] B [文章编号] 1673-9701（2017）34-0104-03 　　Analysis on the clinical effect of compound ipratropium bromide atomization in the patients with acute exacerbation of chronic obstructive pulmonary disease 　　WANG Qin HUANG Xiaohong ZHU Qiqi 　　Department of Geriatrics，Jiujiang NO.1 Peoples Hospital in Jiangxi Province，Jiujiang 332000， China 　　[Abstract] Objective To analyze the clinical effect of compound ipratropium bromide atomization in the patients with acute exacerbation of chronic obstructive pulmonary disease. Methods From May 2014 to May 2017， 80 patients with acute exacerbation of COPD who were admitted to our hospital were selected randomly. These patients were divided into control group（budesonide atomization treatment，n=40）and treatment group（budesonide + compound ipratropium bromide atomization treatment，n=40）according to the treatment methods. The dyspnea score， blood gas analysis index level， respiratory function index level， and adverse reactions were statistically analyzed in both groups. Results In the treatment group， the scores of dyspnea， the decrease degree of PaCO2 level and the increase of PaO2 level were higher than those in the control group（P0.05）. The increase degrees of FEV1， FEV1% and FVC were significantly higher than those in the control group（P0.05）. Conclusion Compound ipratropium bromide atomization has a favorable clinical effect in the patients with acute exacerbation of chronic obstructive pulmonary disease， which can effectively relieve dyspnea and improve blood gas analysis and pulmonary function in patients， and is wo