头孢唑肟钠治疗慢性支气管炎急性发作临床疗效观察.docVIP

头孢唑肟钠治疗慢性支气管炎急性发作临床疗效观察 　　【摘要】目的 探讨慢性支气管炎急性发作期应用头孢唑肟钠治疗的临床疗效。方法 将我院2008年1月～2011年2月收治的慢性支气管炎急性发作患者96例随机分为治疗组、对照组各48例，分别采用头孢唑肟钠、头孢他啶治疗。观察并比较两组临床治疗效果。结果 治疗组48例中治愈38例，好转8例，总有效率95.8%；对照组48例中治愈25例，好转11例，总有效率75.0%。两组总有效率比较有统计学差异（x2=8.36，P0.01）。治疗组咳嗽、痰液量、呼吸次数及湿?音消失或恢复正常平均时间明显早于对照组（P0.05）。治疗期间均未发生明显的药物不良反应。结论 头孢唑肟钠治疗慢性支气管炎急性发作临床疗效好，不良反应少，可迅速缓解急性发作症状、减轻患者痛苦，值得进一步应用。 　　【关键词】支气管炎 急性发作 头孢唑肟钠 头孢他啶 疗效分析 　　中图分类号：R562.21 文献标识码：A 文章编号：1005-0515（2011）5-031-02 　　 Ceftizoxime sodium in the treatment of acute exacerbation of chronic bronchitis, the clinical efficacy 　　ZHANG JuyingTANG Mi 　　（Gaoping District,Nan chong city,sichuang Nan chong 637000 Lung cen ter Hospital） 　　【Abstract】Objective To investigate the application of chronic bronchitis with acute exacerbation of ceftizoxime sodium in the treatment of clinical efficacy. Method to our hospital in January 2008 ~ February 2011 admitted patients with acute exacerbation of chronic bronchitis, 96 patients were randomly divided into treatment group and control group 48 cases, respectively ceftizoxime sodium, ceftazidime treatment. Observe and compare the two sets of clinical effect. Results 48 patients were cured, 38 cases improved in 8 cases, 95.8% total efficiency; the control group 48 cases 25 cases were cured, improved in 11 cases, total effective rate 75.0%. The total effective rate was statistically different (x2 = 8.36, P 0.01). Treatment group, cough, sputum volume, respiratory rate, and moist rales disappeared or returned to normal average time was significantly earlier than the control group (P 0.05). Occurred during treatment were not significant adverse drug reactions. Conclusion ceftizoxime sodium in the treatment of acute exacerbation of chronic bronchitis, clinical efficacy, adverse reactions, can quickly relieve acute symptoms, reduce patient pain, worthy of further applications. 　　【Key words】acute bronchitis Ceftizoxime efficacy of ceftazidime 　　 　　慢性支气管炎属于气道慢性炎症，临床症状以咳嗽、咳痰多见。慢性支气管炎通常同时伴发COPD、肺气肿等，严重影响了患者的劳动能力