多肽合成工艺流程(英文版).pptVIP

* Solid phase peptide synthesis Part II Application of Fmoc/tBu strategy Gábor Mez? Research Group of Peptide Chemistry Hungarian Academy of Sciences E?tv?s L. University Budapest, Hungary Outline Resins; Protecting groups; Synthetic protocol; Monitoring; Cleavage technics; Side reactions; Fmoc/tBu: N H C C H 2 O C N H C H C H 2 C O O C O H C C H 3 C H 3 C H 3 N H C H C O O C H 2 C H 2 O C H 2 O O C C H 3 C H 3 C H 3 C R Fmoc tert-butyl .. piperidine TFA Wang-resin Fmoc-Asp(OtBu)-Tyr(tBu)-Wang resin Type of resins for Fmoc-chemistry There are many different resins and most of t