诺得胶囊降血脂实验及毒性实验研究（毕业学术论文设计）.docVIP

PAGE PAGE 1 诺得胶囊降血脂实验及毒性实验研究 目录 目录……………………………………………………………………………………………1 中文摘要………………………………………………………………………………………2 英文摘要………………………………………………………………………………………3 前言……………………………………………………………………………………………4 正文……………………………………………………………………………………………5 第一部分 诺得胶囊降血脂实验研究 …………………………………………………5 1 实验材料 …………………………………………………………………………5 2 方法与结果 …………………………………………………………………………5 3 讨论与小结 …………………………………………………………………………6 第二部分 诺得胶囊长期毒性实验研究………………………………………………6 1 实验材料 …………………………………………………………………………6 2 方法与结果 …………………………………………………………………………6 3 讨论与小结 …………………………………………………………………………7 参考文献 ……………………………………………………………………………………8 附录 …………………………………………………………………………………………9 综述 ……………………………………………………………………………………9 个人简介 ………………………………………………………………………………13 致谢 …………………………………………………………………………………………14 摘要 诺得胶囊降血脂实验及毒性实验研究 摘要 目的：研究诺得胶囊对高脂血症大鼠的降血脂作用及其毒性作用。方法：①采用脂代谢紊乱模型法，预防性给受试物，并眼球采血测定大鼠血清甘油三酯（TC）、血清总胆固醇（TG）、高密度脂蛋白胆固醇（HDL-C）水平。②动物按体重随机分组，按受试物推荐用量设3个剂量组以及阴性对照组，30d后取脏器做病理学检查以观察其毒性作用。结果：①诺得胶囊灌胃给药能显著降低降低高脂血症大鼠TC水平。②诺得胶囊连续给药30d后，动物无死亡现象，前后体重无显著差异，取高剂量组与空白组脏器做组织病理检查也未见特异性病理改变。结论：诺得胶囊具有降低高脂血症大鼠血清总胆固醇水平的作用并且无明显的毒性作用。 关键词 诺得胶囊、血脂、毒性作用 Study on Nuode capsule falls the blood fats experiment and the toxicity experimental AbstractOb jective：Studies the Nuode capsule to fall the blood fats function and the toxic effect to the hyperlipemia big mouse. Methods：①Uses the fat metabolic disorder modeling, preventive for is tried, and the eyeball picks the blood to determine the big mouse blood serum triglyceride (TC), the blood serum total cholesterol (TG), the high density lipoprotein cholesterol (HDL-C) the level.②The animal groups stochastically according to the body weight, According to receives tries the recommendation amount used to suppose 3 monitoring teams as well as the negative control group, after 30d, takes the internal organs to make the pathology inspection to observe its toxic effect. Results：①The nuode capsule fills the stomach to be able obviously to lower the hyperlipemia big mouse TC level to the medicine. ②after the nuode capsule gives