制药工程专业英语药物研发.pptxVIP

Part sixth Safety evaluation（安全评估）Part sixth Safety evaluation （安全评估）The objective of animal toxicology testing，carried out prior to the administration of a drug to man，is to reject compounds of unacceptable toxicity and to identify potential target organs and timings for adverse effects of the drug.对动物毒理学测试的目标，实施在药品监督管理局把药物用在人身上测试之前，是拒绝不可接受的毒性化合物，并确定为潜在的药物不良反应的靶器官和时序。This means that in early human studies these organs and tissues can be monitored with particular attention.这意味着，在研究这些早期人类器官和组织，可特别注意监测。Part sixth Safety evaluation （安全评估） It is important to establish whether toxic effects are rev