延华胶囊栓剂治疗妊娠期念珠菌性阴道炎疗效的探讨.docVIP

延华胶囊栓剂治疗妊娠期念珠菌性阴道炎疗效的探讨 　　[摘要] 目的:探讨妊娠期念珠菌性阴道炎的最佳治疗方法。方法:将定期产检的180例患病孕妇随机分为三组,延华胶囊栓剂组、制霉菌素组和苏打水擦洗阴道组。同时观察三组的临床疗效。结果:延华胶囊栓剂组治愈率为95.00%(57例),制霉菌素组为83.33%(50例),苏打水擦洗阴道组为53.33%(32例)。三组比较,有显著性差异(P0.05),延华胶囊栓剂组疗效最优。结论:延华胶囊栓剂阴道放药疗效显著,无明显副作用,孕妇易接受,方法简单,用药时间短,是治疗孕期念珠菌性阴道炎较佳的疗法。 　　[关键词] 延华胶囊栓剂;孕期;念珠菌性阴道炎 　　[中图分类号] R71[文献标识码]A [文章编号]1673-7210(2009)07(a)-096-02 　　 　　The therapeutic efficacy of Yan-hua Capsules suppository in the pregnancy women with candida vaginitis 　　TANG Yizhong,MO Keliang,LUO Yufang 　　(Department of Gynecology,the 4th Affiliated Hospital of Guangxi Medical University, Liuzhou 545005,China) 　　[Abstract] Objective: To explore the best treatment of candida vaginitis in pregnancy. Methods: 180 cases were randomly divided into three groups, Yan-hua Capsules suppository group, Nystatin group and Soda water vaginal ecouvillon group, the therapeutic efficacy was observed. Results: The effective rate was 95.00% for Yan-hua capsule suppository(57 cases),83.33% for Nystatin group(50cases),53.33% for Soda water vaginal ecouvillon group(32 cases). There were significantly different in the three groups (P0.05), and the efficacy of Yan-hua Capsules suppository was the best. Conclusion: Yan-hua Capsules suppository has significant efficacy without side effect. This treatment is more acceptable for gravida and easy to operate and it needs less time to recover. It′s an ideal way for treating candida vaginitis. 　　[Key words] Yan-hua Capsules suppository; Pregnancy; Candida vaginitis 　　 　　念珠菌性阴道炎是一种常见的阴道炎,其中80%～90%的病原体为白色念珠菌[1]。孕妇在妊娠期间,特别是妊娠中晚期更易患念珠菌性阴道炎,其发病率约为非妊娠期的3倍。由于孕妇外阴瘙痒,甚至奇痒难忍,烦躁不安,给孕妇精神造成极大的压力与痛苦[2],分娩期通过产道易引起新生儿真菌感染。我院采用延华胶囊栓剂对照制霉菌素、苏打水阴道擦洗治疗,以探讨治疗孕期念珠菌阴道炎安全、有效的方案。 　　1 资料与方法 　　1.1 病例选择 　　2007年3月～2008年3月在我院门诊定期产检的孕妇180例,其中,孕16～28周115例,29～36周65例;年龄20～35岁,平均25.5岁;孕第一胎105例,第二胎以上75例。按数字表随机分为延华胶囊栓剂组(A组)、制霉菌素组(B组)、苏打水阴道擦洗组(C组),每组60例。三组孕妇既往无妇科炎症病史,排除其他妊娠合并症,生活、饮食、起居无特殊安排。 　　1.2 诊断标准 　　1.2.1 临床症状外阴阴道瘙痒,外阴阴道烧灼感刺激,外阴潮红,外阴水肿,外阴表皮脱落,阴道潮红,阴道水肿,以上7个临床症状至少1个。 　　1.2.