旋毛虫期特异性基因的筛选及其高效表达-OIE.PDF

Trichinella spp and clonorchis sinensis Liu Mingyuan OIE Collaborating Centre for Food-Borne Parasite from the Asian-Pacific Region Institute of Zoonosis, Jilin University, China Trichinella spp Infection and infestation of human and animals Life cycle of Trichinella In the world • 150 animals species can be infected • 10030 human cases, estimated more than 10 million people infected. ICT reported 1995-1997. In the world • 0.570 billion Euro in EU, 1 billion US ＄in USA, 20 billion US ＄in China for pig inspection China 0.73 billion European Union pig slaughter USA Russia Mexico South Africa others Pork product in world Trichinellosis in China • 14 mammal animal species infected. • 27 thousand human cases since 1964, 40 millions people with sera-positive (2005, national surveillance). • 0.64 billion pigs for Trichinella inspection per year. 20 millions 10 years ago, 1995 Reservoir for human cases in China 5,7 % 94,3 % Recent outbreaks in Yunnan province, China, 2009 Trichinella species, evolution and migration in China Identified by the PCR and cross breeding ISS531, ISS532, ISS533, ISS534, ISS535