联合用药治疗肺心病难治性心力衰竭的的疗效观察.docVIP

联合用药治疗肺心病难治性心力衰竭的的疗效观察 　　[摘要] 目的 探讨治疗肺心病难治性心力衰竭更为有效的方法。方法 将患者60例,按入院治疗的先后顺序随机分为观察组36例和对照组24例。两组均采用常规治疗,包括持续低流量吸氧、控制感染、祛痰平喘、强心利尿等综合治疗。观察组在常规治疗的基础上,同时将小剂量肝素50 mg、硫酸镁注射液2.5g、消心痛注射液20mg分别加入液体中静脉点滴,1次/d,10d为1个疗程。结果 经χ2检验,提示观察组疗效明显优于对照组,具有显著性差异(P0.05)。结论 肺心病难治性心力衰竭在常规治疗无效时加用小剂量肝素和硫酸镁以及消心痛可减轻心衰的临床症状,改善心功能。 　　[关键词] 肺心病;难治性心力衰竭;小剂量肝素;硫酸镁;消心痛;联合用药 　　[中图分类号] R587.2 [文献标识码] A[文章编号] 1673-9701(2010)02-157-02 　　 　　Clinical Efficacy of Combined Drug in Treatment of Pulmonary Heart Disease Refractory Heart Failure 　　WANG Wenli 　　Department of Clinical Medical College of Jiaozuo,Jiaozuo 454150,China 　　 　　[Abstract] Objective To investigate the treatment of refractory heart failure with pulmonary heart disease more effective approach. Methods Sixty patients admitted to hospital according to the order of 36 cases were randomly divided into two groups and the control group 24 cases. Both groups received routine therapy,including continuous low-flow of oxygen,infection control,expectorant asthma,cardiac diuretic such comprehensive treatment. Observer group on the basis of conventional therapy,while low-dose heparin 50 mg,magnesium sulfate injection 2.5g,isosorbide dinitrate injection 20mg intravenous fluids were added,1/d,10 days a course of treatment. Results The χ2 test suggesting that the observation group was superior efficacy than the control group with significant difference(P0.05). Conclusion Pulmonary heart disease with refractory heart failure when conventional treatment fails with a small dose of heparin and magnesium sulfate,and isosorbide dinitrate reduce the clinical symptoms of heart failure and improve cardiac function. 　　[Key words] Pulmonary heart disease;Refractory heart failure;Low-dose heparin;Magnesium sulfate;Isosorbide dinitrate;Combination therapy 　　 　　肺心病是较为常见的一种疾病,部分患者反复并发心力衰竭,治疗难度较大。本文总结了近两年笔者在工作中遇到的一些难治性心力衰竭患者,在常规治疗(抗炎、解痉、利尿、洋地黄应用)的基础上,采用联合用药即小剂量肝素+硫酸镁+消心痛治疗后取得较好疗效。现将观察结果报道如下。 　　 　　1资料与方法 　　 　　1.1一般资料 　　本组患者60例,均为我院附属医院心内科2007年1月～12月间入院治疗的肺心病