成人肺朗格汉斯细胞组织细胞增生症2例报道并文献复习-内科学专业论文.docx

独创性声明 本人声明所呈交的学位论文是我个人在导师指导下进行的研究工作及取得的 研究成果。尽我所知，除文中已经标明引用的内容外，本论文不包含任何其他个 人或集体已经发表或撰写过的研究成果。对本文的研究做出贡献的个人和集体， 均已在文中以明确方式标明。本人完全意识到本声明的法律结果由本人承担。 学位论文作者签名： 日期： 年 月 日 学位论文版权使用授权书 本学位论文作者完全了解学校有关保留、使用学位论文的规定，即：学校有权保 留并向国家有关部门或机构送交论文的复印件和电子版，允许论文被查阅和借阅。本 人授权华中科技大学可以将本学位论文的全部或部分内容编入有关数据库进行检索， 可以采用影印、缩印或扫描等复制手段保存和汇编本学位论文。 本论文属于 保密□， 在 年解密后适用本授权书。 不保密□。 （请在以上方框内打“√”） 学位论文作者签名： 指导教师签名： 日期： 年 月 日 日期： 年 月 日 目 录 中英文缩略词表 ································································································· 1 摘 要·················································································································· 3 ABSTRACT 5 引 言·················································································································· 7 病例报道 ······································································································· 8 文献复习 ····································································································· 13 参考文献 ····································································································· 19 综 述················································································································ 23 致 谢················································································································ 36 中英文缩略词表 英文缩写 英文全称 中文名称 TBLB Transbronchial Lung Biopsy 经支气管肺活检 BALF broncho-alveolar lavage fluid 支气管肺灌洗液 CT Computed tomography 电子计算机断层扫描 HRCT High-resolution computed tomography 高分辨率电子计算机断层扫描 LIP Lymphocytic interstitial pneumonia 淋巴细胞间质性肺炎 LAM Lymphangioleiomyomatosis 淋巴管平滑肌瘤病 LCH Langerhans cell histiocytosis 朗格汉斯组织细胞增多症 MS-LCH Multisystemlangerhans cell histiocytosis 多系统朗格汉斯组织细胞增多症 SS-LCH Single systemlangerhans cell histiocytosis 单系统朗格汉斯组织细胞增多症 PLCH Pulmonary Langerhans histiocytosis 肺朗格汉斯组织细胞增多症 TSC Tuberous sclerosis complex 结节性硬化症 LC Langerhans cell 朗格汉斯细胞 APC antigen presenting cell 抗原递呈细胞 DI diabetes insipidus 尿崩症 2-CDA 2-chlorodeoxyaden