最新碘-125放射粒子组织间植入治疗恶性肿瘤.pptVIP

Thus the overall responding rate ended up at 61.3% with local tumor control rate was 90.3%. Median survival time for the whole group was 10.31 months. * Here is the image of one patient. This is pre-implant CT result, the red arrow showed the location of the mass. Now is the post implant image, we can see the decreased size of the mass and seeds were in place. In terms of complications, there is no serious complication encountered. In drug-seeds combined group there is some reversible side effects like leukopenia and renal function impairment. We are extending our experience of iodine 125 into the field of pancreatic cancer after promising results on liver and lung malignancies. Here is some technical tips to share. Fast the patient and inhibit pancreatic secretion. Transgress the stomach is safer than intestine, keep in mind to avoid puncturing colon. Our preliminary results showed drug-seeds combined therapy had better outcome which need to be validated in the future. Time to draw the conclusion, CT-guided brachytherapy using iodine 125 seeds implantation appeared to be safe, effective, less complicated and could produce adequate pain relief for treating unresectable pancreatic cancer. Thanks all of you for kind your attention. Iodine-125 Therapy in Advanced Pancreatic Cancer Results Change of Karnofsky physical score % (cases) Karnofsky score 100 90 80 70 60 50 Pre-op 0（0/31） 3.2（1/31） 9.7(3/31) 41.9(13/31) 35.5(11/31) 9.7（3/31） Post-op 0（0/31） 48.4(15/31) 16.1(5/31) 9.7(3/31) 19.4(6/31) 6.4(2/31) Results Change of pain score % (cases) Iodine-125 Therapy in Advanced Pancreatic Cancer No Pain (%) Mild Pain (%) Moderate Pain (%) Severe Pain (%) Pre-op 6.5（2/31） 22.5(7/31) 32.3(10/31) 38.7(12/31) Post-op 38.7(12/31) 32.3(10/31) 16.1(5/31) 12.9(4/31) Results Overall responding rate (CR+PR) =61.3% Local tumor control rate was 90.3% Median survival time for the whole group was 10.31 months Median survival time for pure seeds imp