生物化学IILectureFattyaidmetabolismwebversion.pptVIP

Fatty acid metabolism – topics Role of lipases – breakdown of triglycerides and phospholipids Activation of fatty acids for the β-oxidation cycle (CoASH) Transport into the mitochondria (carnitine) β-oxidation pathway Even chain saturated FA Unsaturated FA Odd numbered FA Role of biotin and Vit B12 Energy calculations Starvation Energy sources for exercise Fatty acid oxidation-energy from lipids Long chain FA serve as main source for animals: FA are oxidized and broken down to AcCoA. The release of electrons (NADH) drives ATP synthesis ? Energy The production of AcCoA feeds the TCA cycle ? En