Atherosclerosis. 2012 Jan 18. [Epub ahead of print]英文资料.pdf

G Model ATH-12416; No. of Pages 10 ARTICLE IN PRESS Atherosclerosis xxx (2012) xxx–xxx Contents lists available at SciVerse ScienceDirect Atherosclerosis j o u r n a l h o m ep a g e : w w w. elsev /locate/atherosclerosi s Review The magic and mystery of MicroRNA-27 in atherosclerosis Wu-Jun Chen a,b , Kai Yin a,c , Guo-Jun Zhao a,d , Yu-Chang Fu e , Chao-Ke Tang a,∗ a Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Life Science Research Center, University of South China, Hengyang, Hunan 421001, China b Institute of Pharmacy and Pharmacology, University of South China, Hengyang 421001, China c The Department of Diagnostics, University of South China, Hengyang 421001, China d Department of Histology and Embryology, University of South China, Hengyang 421001, China e Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294-0012, USA a r t i c l e i n f o a b s t r a c t Article history: Atherosclerosis (As) is now widely appreciated to represent a chronic inflammatory reaction of the vas- Received 10 November 2011 cular wall in response to dyslipidemia and endothelial distress involving the inflammatory recruitment Received in revised form 10 January 2012 of leukocytes and the activation of resident vascular cells. MicroRNAs (miRNAs) are a group of endoge- Accepted 11 January 2012 nous, small (∼22 nucleotides in length) non-coding RNA mole