以蒙特利尔认知评估量表（MoCA）分析血管源性轻度认知障碍的神经心理学特征.docVIP

以蒙特利尔认知评估量表（MoCA）分析血管源性轻度认知障碍的神经心理学特征 世界中西医结合杂志2010年第5卷第8期w.ddJournal.fIntegratedTraditi.nalandWestemMedicine2010,V.1.5,N..8681? ? 临床研究? 以蒙特利尔认知评估量表(MoCA)分析血管源性 轻度认知障碍的神经心理学特征 侯小兵张允岭高芳陈宝鑫陶冶金香兰 【摘要】目的利用蒙特利尔认知评估量表(MoCA)探讨血管源性轻度认知障碍(vMCI)的神 经心理学特征,为早期发现,早期诊断,早期干预vMCI提供借鉴之处,并对敏感亚项认知域进行分 析,以期探讨此类疾病的发生,发展规律.方法将107例vMCI患者的神经心理学检查结果进行各 认知领域的亚项分析.结果vMCI各认知域障碍发生率的不一致,MoCA中的各认知域与总分的相 关性分析表明,注意,视空间与执行能力与量表总分密切相关,同时也表明,此次调研患者认知域损害 以注意,视空间与执行能力损害为主.结论MoCA中的相关子域能够很好地筛查出vMCI;MoCA中 的延迟记忆及执行能力与总分相关性较强,说明vMCI患者的执行能力与延迟记忆能力密切相关. 【关键词】血管源性轻度认知障碍;蒙特利尔认知评估量表;神经心理学特征 AnalysisofNeurOpsycholOgicalCharacteristicsofVascularMildCognitive ImpairmentwithMontrealCognitiveAssessment(MoCA) H0UXiao—bing,ZHANGrun—ling,GAOFang,CHENGBao—xin,TA0Ye,JINXiang—lan (DongfangHospitalofBeijingUniversityofTraditionalChineseMedicine,Beijing100078) 【Abstract】ObjectiveToexploretheneuropsychologicalcharacteristicsofvascularmildcognitive impairment(vMCI)withMontrealCognitiveAssessment(MoCA)SOastoprovidetheevidencesforearlydis— covery,diagnosisandinterventionofvMCI,analyzethesub—domainofcognitivesensitivityanddiscussthe lawofoccurrenceanddevelopmentofthisdisease.MethodsThesub—typeanalysiswasconductedineach cognitivedomainfortheneuropsychologicalresultsof107casesofvMCI.ResultsTheincidencesweredif- ferentintheimpairmentofeachcognitivedomainofvMCI.Itwasindicatedbytherelevanceanalysisbetween eachcognitivedomainandtotalscoreinMoCAthatattention,visualspaceandexecutivecapacitywererele— vantcloselywiththetotalscoreinthescale.Meanwhile,itwasfoundthatintheinvestigationofcognitivedo— maindamage,theattention,visualspaceandexecutivecapacitywerechieflyinvolved.ConclusionTherele— vantsub—-domaininMoCAcanwellscreenvMCI.TheretardedmemoryandexecutivecapacityinMoCAare stronglyrelevantwiththetotalscore,whichindicatesthattheexecutivecapacityofvMCipatientiscloselyrel— evantwithretardedmemory. 【Keywords】VascularMildCognitiveImpairment(vMCI);MontrealCognitiveAssessment(MoCA); NeuropsychologicalCharacteristics 随着我国人口的老龄化,老年期痴呆占中国神 经精神疾病负担伤残调