菁染料及其功能化纳米材料在生物分析和近红外荧光成像方面应用研究进展.pdfVIP

Advances in Analytical Chemistry 分析化学进展, 2016, 6(4), 109-115 Published Online November 2016 in Hans. /journal/aac /10.12677/aac.2016.64017 Research Progress in Cyanine Dyes and Their Functionalized Nanocomposites Used for Bioanalysis and Near-Infrared Molecular Fluorescent Imaging Hongxiang Huang Department of Macromolecular Science of Fudan University, State Key Laboratory of Molecular Engineering of Polymers, Shanghai th st th Received: Oct. 11 , 2016; accepted: Nov. 1 , 2016; published: Nov. 7 , 2016 Copyright © 2016 by author and Hans Publishers Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). /licenses/by/4.0/ Open Access Abstract Cyanine (Cy) compounds can produce strong fluorescent emission in the near infrared region after radiation and be easily modified with various substituents, thus they have been recently widely used as fluorescent probes to bind with bio-molecules, cells and tissues. The as-prepared lumi- nescent materials have provided a facile route for the bioanalysis, molecular fluorescent imaging and clinicopathologic analysis, especially for the tumour diagnosis and treatment. In this work, we reviewed the latest achievement of applications of several well-known cyanine derivatives such as Cy3, Cy5, Cy7, Cy3.5, Cy5.5, and their bio-nanocomposites produced with inorganic nanoparticles as luminescent probes in the fields of bioanalysis and near infrared molecular imaging. Keywords Cyanine, Bioanalysis, Near Infrared Image, Bio-Nanocomposite, Fluorescence 菁染料及其功能化的纳米材料在生物分析和 近红外荧光成像方面的应用研究进展 黄红香 文章引用: 黄红香. 菁染料及其功能化的纳米材料在生物分析和近红外荧光成像方面的应用研究进展[J].