光动力疗法联合卡介菌多糖核酸注射液治疗尖锐湿疣的临床疗效观察.docVIP

獅力棚关菌多臟節繼 2018-03-20 01:26:12中国现代医生2018年1期 刘海文李爱莉 两组CA患者疗效比较［%（，//，，）］ 组別 71 治愈 4^ 治疗组 79 93.67(74/79) 6.33( 对照组 78 83.33(65/78) 16.67( X2值 4.132 4. P 0.05 c 表1两组CA患者一般资料比较 组别 n 性別 男/女 年龄 （岁） 病程 （月） 疣体数 （个） 治疗组 79 40/39 32.00±9.61 3.43±0.87 2.49±0.5^ 对照组 78 39/39 31.99±9.59 3.45±0.89 2.51 ±0.5( P 0.05 0.05 0.05 0.05 ［ ］u的探讨光动力疗法联合卡介尚多糖核酸注射液治疗尖锐湿疣的临床疗效。方法将门 诊157例尖锐湿疣患者按就诊的先后顺序随机分为两组。治疗组79例采用光动力疗法联合卡介菌多 糖核酸注射液治疗，对照组78例单用光动力疗法治疗，末次治疗后连续随访6个月。第1个月每周 随访1次，以后每71随访1次，连续6个月观察治疗效果及复发情况。结果治疗组的治愈率和笈发 率分别为93.67%和6.33%，对照组的治愈率和M发率分别为83.33%和16.67%，两组的治愈率和复 发率比较差异均有统计学意义（P0.05）。两组均未出现明显的不以反应，偶有患者出现轻度灼热感， 个別出现轻度糜烂。结论光动力疗法联合卡介菌多糖核酸注射液治疗尖锐湿疣可以提髙疗效，减少 复发率和副作用，值得临床推广。 ［关键同］尖锐湿疣；光动力疗法；5-氨基酮戊酸；卡介菌多糖核酸注射液 ［屮图分类号］R752.53 ［ ］A ［文草编号］1673-9701 (2018) 01-0025-04 Observation of the clinical effect of photodynamic therapy combined with BCG polysaccharide and nucleic acid injection in the treatment of condyloma acuminatum LIU Haiwen LI Aili Department of Dermatology, Dalian Skin Disease Hospital, Dalian 116021, China ［Abstract］ Objective To investigate the clinical efficacy of photodynamic therapy combined with BCG polysaccharide and nucleic acid injection in the treatment of condyloma acuminatum. Methods 157 patients with condyloma acuminatum in the outpatient were randomly divided into two groups according to the order of treatment. 79 patients in the treatment group was given photodynamic therapy combined with BCG polysaccharide and nucleic acid injection for the treatment. 78 patients in the control group were treated with photodynamic therapy alone. The follow-up period was 6 months continuously after the last treatment. The follow-up visit was carried out once in a week in the first month, followed by the follow-up visit once a month. The curative effect and recurrence were observed for 6 months continuously. Results The cure rate and recurrence rate in the treatment group were 93.67% and 6.33%, and the cure rate and recurrence rate in the control group were 83.33% and 16.67%. The cure rat