加州大学伯克利分校有机化学第七章.pptVIP

? University of California ? Univesity of California Chapter 7: SN1, E1, E2, notjust SN2 Mechanism Incomplete Racemization The Strong Effect of Polar Solvents on the SN1 Reaction Hyperconjugation X-Ray Structure of the 1,1-Dimethylethyl Cation(Laube, 1993) Summary Mechanism of the E1 Reaction Bimolecular Elimination E2 Mechanism of the E2 Reaction E2 in Cyclic Systems Hindered Base Ensures E2 Factors that Affect the Competition between SN and E An alkene 1. Mechanism: SN2 SN1 E2 E1? 2. At lower temperatures one of the following ratios will increase: SN2 / SN1