抗肿瘤英药(英文版）.pptVIP

Anticancer Drugs Dr.Qamar Barakzai Department of Pharmacology Ziauddin Medical University Karachi.Pakistan * “CANCER” Refers to a Malignant neoplasm (New growth) Cancer cells can manifest: Uncontrolled Proliferation. Loss of function due to lack of ability to differentiate. Invasiveness. The ability to metastasize. Cancer arises as a result of a series of genetic changes in the cell, the main genetic lesions being: Inactivation of tumor suppressor genes. The activation of oncogenes. Antineoplastic agents Are cytotoxic not tumoricidal Only kill cells during mito