颅内高一血压（英文）.pptVIP

Intracranial Hypertension Gene Y. Sung, M.D., M.P.H. Director, Neurocritical Care and Stroke Division University of Southern California Intracranial Pressure Physiology Monro-Kellie Doctrine (1783/1824) 1. Rigid container 2. Liquid contents are incompressible 3. Mass must be displaced Intracranial Pressure Physiology Cranial Contents Total Volume 1300-1500 cc Brain ~ 80% gray matter/ white matter CSF ~ 10% Intraventricular 50% 75 cc Subarachnoid 50% 75 cc Blood ~ 10% Arterial 30% 45cc Venous 70% 105cc Intracranial Pressure Pathophysiology Blood – epidural, subdural, subarachnoid,