箭舌豌豆和京大戟化学成分等及生物活性研究1.docxVIP

兰州人学硕上学位论文 兰州人学硕上学位论文 李文海 ABSTRACT The Hcia sativa linn，a perennial herb，is genus of family Papilionaceae．There are about 200 species all OVer the world which are widely distributed in Northern Hemisphere temperate regions and South America．In China，there are 43 species and 5 mutations which are widely spreaded all across the country,espacially in Northwest，North and Southeast．They have long been used as green manure，also are fine pastures．Previous studies on Hcia sativa linn indicated that it contained flavonol， flavonol glycoside，steroid and terpenes．It is also reported that its extract was ever used t0仃eat tumor． The Euphorbia pekinensis Rupr is a genus of family Euphorbiaceae tribe Euphorbia and a perennial herb．There are about 8000 species all OVer the world which are widely distributed in tropic or subtropic zone．The genus Euphorbia is composed of more than 360 species in China which are widely spreaded in provinces south of Yangzi River．The major actively functional constituents include alkaloid， diterpenoids and triterpenoids．Research shows diterpenoids have anti—tumor, antibiosis，antiviral activies． In order to explore more medical potential plants of Hcia species and Euphorbia species，and to exploit new resources of Chinese traditional medicine，the chemical constituents of these two plants have been studied．The compounds were isolated by means of silica gel and Sephadex LH-20 gel columm chromatography, preparative thin layer chromatography and recrystallization etc．The structures of these compounds were elucidated by spectroscopic methods(IR，El—MS，HR·ESI—MS， 1H NMR，13C NMR，DEPT,1H_lH cosY,HMBC，HSQC etc．)．From Hcia sativa linn， ten compounds were isolated and elucidated，one of them is new compound，and twenty compounds were isolated and elucidated from Euphorbia pekinensis Rupr and three of them were ilew compounds．one triterp