2018意大利酒精学会意见书：急性酒精中毒和酒精中毒戒断综合征的诊断和治疗.pdfVIP

Internal and Emergency Medicine /10.1007/s11739-018-1933-8 CE - ORIGINAL Diagnosis and treatment of acute alcohol intoxication and alcohol withdrawal syndrome: position paper of the Italian Society on Alcohol 1,2 3 4 5 5 6 Fabio Caputo  · Roberta Agabio  · Teo Vignoli  · Valentino Patussi  · Tiziana Fanucchi  · Paolo Cimarosti  · 6 7 8 9 10 11 Cristina Meneguzzi  · Giovanni Greco  · Rafaella Rossin  · Michele Parisi  · Davide Mioni  · Sarino Arico’  · Vincenzo Ostilio Palmieri12 · Valeria Zavan13 · Pierluigi Allosio14 · Patrizia Balbinot15 · Maria Francesca Amendola16 · Livia Macciò17 · Doda Renzetti18 · Emanuele Scafato19 · Gianni Testino15 Received: 26 April 2018 / Accepted: 22 August 2018 © Società Italiana di Medicina Interna 2018 Abstract The chronic use of alcohol can lead to the onset of an alcohol use disorder (AUD). About 50% of subjects with an AUD may develop alcohol withdrawal syndrome (AWS) when they reduce or discontinue their alcohol consumption and, in 3–5% of them, convulsions and delirium tremens (DTs), representing life-threatening complications, may occur. Unfortunately, few physicians are adequately trained in identifying and treating AWS. The Italian Society on Alcohol has, therefore, imple- mented a task force of specialists to draw up recommendations for the treatment of AWS with the following main results: (1) while mild AWS may not require treatment, moderate and severe AWS need to be pharmacologically treated; (2) out- patient treatment is appropriate in patients with mild or moderate AWS, while patients with severe AWS need to be treated as in-patients; (3) benzodiazepines, BDZs are the “gold standard” for the treatm