中药封包与双氯芬酸钠对膝关节骨性关节炎临床疗效对比分析.PDFVIP

·350 · 沈阳医学院学报 Journal of ShenyangMedical College 第 18卷 第5期 2016年9月 中药封包与双氯芬酸钠对膝关节骨性关节炎临床疗效对比分析 王天旭 ，邬波1 2* （1.辽宁中医药大学研究生学院，辽宁 沈阳 110847；2 沈阳市骨科医院综合外科） ［摘要］目的：对比中药封包与双氯芬酸钠治疗膝关节骨性关节炎 （KOA）的临床疗效。方法：将我院2015 年1 月至2015 年7 月收治的88 例KOA 患者根据随机数字表分为治疗组和对照组。治疗组采用中药封包治疗，对照组采用双氯芬酸钠常 规治疗，2 组根据 《中药新药临床研究指导原则》及西安大略大学和麦克马斯特大学骨关节炎指数 （WOMAC ）标准进行 判定，并对比2 组治疗疗效。结果：2 组患者在接受治疗后，病情均有所缓解。治疗组临床控制5 例，显效24 例，有效13 例，无效2 例，总有效率95.45% ；对照组临床控制2 例，显效11例，有效24 例，无效7 例，总有效率84.09%。2 组患者的 WOMAC 评分均显著低于治疗前，且治疗组的临床效果更为显著，差异有统计学意义 （P0.05 ）。结论：给予KOA 患者采 用中药封包治疗，疗效良好，值得临床推广。 ［关键词］膝关节骨性关节炎；中药封包；双氯芬酸钠缓释片 ［中图分类号］R274.943 ［文献标识码］A ［文章编号］1008-2344（2016 ）05-0350-03 doi：10.16753/ki. 1008-2344.2016.05.009 ComparisonofClinicalCurativeEffectBetweenTraditionalChineseMedicinePacketandDiclofenac SodiumonKneeOsteoarthritis 1 2* WANG Tianxu ，WU Bo （1.Graduate School of Liaoning University of Traditional Chinese Medicine ，Shenyang 110847，China ；2.The Comprehensive Surgery ，Orthopaedic Hospital of Shenyang） ［Abstract ］Objective：To compare the clinical curative effect of traditional Chinese medicine packet and diclofenac sodium treatment on knee osteoarthritis （KOA）. Methods：A total of 88 patients with KOA according to random number table were randomly divided into treatment group and control group. Treatment group was treated with traditional Chinese medicine packet ，the control group recened diclofenac sodium conventional treatment. Traditional Chinese medicine new medicine clinical research guiding principles and Womac standard was used to identify treatment efficacy. Results：Two groups of patients after treatment ，the illness were eased. Treatment group clinical control in 5 cases ，24 cases were markedly effective ，effective 13 cases ，2 had no effect ，the total effective rate was 95.45%. Control group clinical control in 2 cases ，11 cases were markedly effective ，effective 24 cases ，7 had n