raas系统研究的新热_陈明(英文版）.pptVIP

RAAS系统研究的新热点(The Update Of RAAS Research) 重庆医科大学附属第一医院 心内科 陈明 2009-4，广州 The hot research of RAAS Intracellular angiotensin II Ang II receptors,new agonist and antagonist ACE2 and ACE2 activator Renin and renin inhibitor RAAS and cardiac arrhythmia Brain angiotensin II Classical circulating RAAS New expanded view of RAAS RAAS:from circulation to tissue,then intrcellular intracellular angiotensin II ACE is a multifunctional enzyme equally important in the metabolism of vasodilator and antifibrotic peptides. As the membrane-bound form, ACE functions as a “receptor” that initiates intr