免疫细胞功能检测在恶性肿瘤患者外周血中的 表达和临床意义.pdfVIP

Hans Journal of Biomedicine 生物医学, 2017, 7(3), 54-58 Published Online July 2017 in Hans. /journal/hjbm /10.12677/hjbm.2017.73009 Expression of Immune Cell Function in Peripheral Blood of Patients with Malignant Tumor and Its Clinical Significance 1 1 1* 1 2 1 1 Qin Ge , Guodong Xie , Jing Cai , Jizhong Zhao , Jibin Liu , Baixia Yang , Juanjuan Cui , Chunxia Chu1 1 Department of Radiotherapy, Tumor Hospital of Nantong, Nantong Jiangsu 2 Biotherapy Center, Tumor Hospital of Nantong, Nantong Jiangsu nd th th Received: Jun. 22 , 2017; accepted: Jul. 9 , 2017; published: Jul. 12 , 2017 Abstract Objective: To investigate the clinical value of immune cell in peripheral blood of patients with ma- lignant tumor, and to explore its clinical value in the diagnosis and treatment of cancer patients. Methods: 60 cases of cancer patients, including 20 cases of esophageal cancer, lung cancer in 20 cases, 10 cases of nasopharyngeal carcinoma, other tumors (including laryngeal cancer in 1 case, tongue cancer in 1 case, breast cancer in 3 cases, 1 case of skin malignant melanoma, rectal cancer 4 cases) and 20 normal control group peripheral blood T lymphocyte subsets percentage, B lym- phocyte percentage, NK cell percentage, compared with the differences of normal control group. Results: The percentage of total T lymphocytes CD3+, assisted/induced T lymphocyte CD4+ and helped inhibited T lymphocyte ratio CD4+/CD8 in peripheral blood of tumor patients was signifi- cantly lower than that of healthy group (P 0.05). The percentage of inhibition cytotoxicity T lymphocyte CD8+ was slightly highe