糖皮质激素在实验性变态反应性脑脊髓炎中对调节性t细胞的作用.docxVIP

糖皮质激素在实验性变态反应性脑脊髓炎中对调节性T细胞的作用 【关键词】糖皮质激素；，脑脊髓炎，自身免疫性，实验 性；，T 细胞；,F0XP3；,IL Effect of glucocorticoid on CD4+CD25+ regulatory T cells in mice with experimental autoimmune encephalomyelitis [Abstract] AIM： To investigate the modification by glucocorticoid on CD4+CD25+ regulatory T cells in mice with experimental autoimmune encephalomyelitis (EAE). METHODS： Glucocorticoid or placebo (control group) was injected into Balb/c mice that had been immuni^ed with bovine myel in basic protein (MBP) extracted from the fresh spinal cord of OX. CD4+CD25+ regulatory T cell specific FOXP3 and blood IL10 were