胰岛素类似物在慢性肾功能不全患者中的应用..ppt

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2019-03-06 发布于湖北
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胰岛素类似物在慢性肾功能不全患者中的应用..ppt

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THANKS！ Africa: 78% of people with diabetes are undiagnosed Europe: the highest prevalence of type 1 diabetes in children MENA中东北非－Middle East and North Africa: 6 of the top 10 countries by diabetes prevalence NAC北美加勒比海地区－North America and Caribbean: 1 adult in 10 has diabetes SACA中南美洲－South and Central America: 12.3% of all deaths were due to diabetes South-East Asia: almost one-fifth of the world‘s people with diabetes live in just seven countries，包括印度 Western Pacific: 132 million adults have diabetes, the largest number of any region，包括中国 * * * * A: Plasma free insulin levels after subcutaneous injection of 0.2 U/kg regular insulin (□) and insulin lispro (?) in type 1 diabetic patients with overt diabetic nephropathy. Thick lines indicate free insulin concentrations; thin lines indicate fitted polynomial function of sixth order. Data represented are means ± SE. B: Plasma free insulin levels after injection of 0.2 U/kg regular insulin (?) and insulin lispro (○) in type 1 diabetic patients without diabetic nephropathy. Thick lines indicate free insulin concentrations; thin lines indicate fitted polynomial function of sixth order. C: Fitted polynomial function of sixth order to glucose infusion rate after subcutaneous injection of 0.2 U/kg regular insulin (heavy black line) and insulin lispro (dotted line) in type 1 diabetic patients with overt diabetic nephropathy. Thin lines indicate glucose infusion rate original registration. D: Fitted polynomial function of sixth order to glucose infusion rate after subcutaneous injection of 0.2 U/kg regular insulin (heavy black line) and insulin lispro (dotted line) in type 1 diabetic patients without diabetic nephropathy. Thin lines indicate glucose infusion rate original registration. * * 胰岛素类似物在慢性肾病中的应用高洪伟北京大学第三医院内分泌科在中国，发病率逐年上升亚洲高发。发达国家第三大非传染病中国糖尿病患病率变化时间对象标准患病率% 备注 1980年 14省市30万我国标准 0.67 1994年 19省市21万（25~64岁） WHO1985 DM：2.51 IGT：3.2 1996年 11省市4万（20-75岁） WHO1985 DM：3.21 IGT：4.76 分层抽样 2007