- 1、本文档共48页,可阅读全部内容。
- 2、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
- 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
查看更多
课件:型糖尿病全球防治指南新特点.ppt
糖酐酶抑制剂类应用要点 Use α-glucosidase inhibitors as a further option. They may also have a role in some people intolerant of other therapies. Systematic reviews of the α-glucosidase inhibitors have not found reason to recommend them over less expensive and better tolerated drugs. 胰岛素治疗要点 时机; Begin insulin therapy when optimized oral glucose-lowering drugs and lifestyle interventions are unable to maintain blood glucose control at target levels--------generally when DCCT-aligned HbA1c has deteriorated to 7.5 % (confirmed) on maximal oral agents. 可继续联用 metformin. Additionally continue sulfonylureas when starting basal insulin therapy. α-Glucosidase inhibitors may also be continued.. 目标血糖: Aim for pre-breakfast and pre-main-evening-meal glucose levels of 6.0 mmol/l(110 mg/dl); 胰岛素治疗要点 三种模式; a basal insulin once daily such as insulin detemir, insulin glargine, or NPH insulin (risk of hypoglycaemia is higher with the last), or. twice daily premix insulin (biphasic insulin) particularly with higher HbA1c, or. multiple daily injections (meal-time and basal insulin) where blood glucose control is sub-optimal on other regimens, or meal-time ?exibility is desired. 调节方法; Initiate insulin using a self-titration regimen (dose increases of 2 units every 3 days) or by weekly or more frequent contact with a health-care professional 注射部位; abdominal area (most rapid absorption) or thigh (slowest), with the gluteal area (or the arm) as other possible injection sites. 选择皮下注射部位 胰岛素治疗利益 The evidence from UKPDS that insulin was among the glucose-lowering therapies which, considered together, reduced vascular complications compared with ‘conventional’ therapy. Intensified insulin therapy in Type 2 diabetes has been shown to improve metabolic control, improve clinical outcomes、and increase fexibility. Pump therapy in Type 2 diabetes is potential option in highly selected patients or in very individual settings. 全面控制心血管危险因素 控制血压及降压药的选用 ACE-inhibitors and A2RBs may offer some advantages over
文档评论(0)